UMD IP-based Startups

Advanced IRIS Oxides measures, analyzes, and reports on soil reduction in wetlands. IRIS – is an acronym for Indicator of Reduction In Soils. 

Aeroseed's mono-wing rotorcraft mimics a solution discovered in the plant kingdom and implemented on a highly maneuverable aircraft, the Roboseed.

Alchemity is transforming greenhouse gasses and wasted resources into valuable chemicals and fuels with modular turn-key reactor system.

AlphaTrek develops unique state of the art solutions utilizing Context, and help make life better for the users and the community

AmpX Technologies designs and builds next-generation power electronics for energy conversion.

AquaLith manufactures next-generation batteries and battery materials. AquaLith’s capabilities significantly expand lithium-ion energy density beyond anything currently on the market.

To better the lives of patients suffering from rare metabolic disorders. Archimedes is devoted to developing rapid and accurate point-of-care diagnostic devices to optimize the treatment our patients at-home and in the clinic.

At Behavioral Activation Tech, we're bringing clinically proven techniques for the treatment of depression directly to those who need it most, using apps delivered on users' existing mobile phones.

Bolston Technology provides peace of mind and survival options for citizens and professionals who are exposed to fire threats.

BuildSci Analyst is an interactive Asset Management platform for building Facility Managers. The BuildSci Analyst is a platform for facility managers to “train” buildings to be better versions of themselves. 

Carbon Plus is the developer of a novel way to reduce the cost and energy needs for carbon fiber.

Ceracool is the developer of radiative cooling paint, an energy-saving paint that can reduce the temperature of buildings throughout the day.

Decision Point Analytics assists governments and organizations model and understand systemic risk in their organization and supply chains.

e4usa aims to provide a high-quality engineering curriculum that can be taught by any high school teacher to students who have Algebra I at least as a co-requisite, helping to build the workforce of tomorrow.

Plate Vision is a regulation sized home plate that calls balls and strikes and delivers the results in real-time to a field umpire, coach, and parent. Freestate Optics, a Maryland based company, invented the Plate Vision system and holds the respected patents associated with the system. 

Gelectric specializes in an innovative electrically adhesive gel patch that securely adheres to tissue surfaces, enabling targeted treatment where standard sutures fail. Harnessing the phenomena of electroadhesion, this groundbreaking technology has the potential to transform tissue repair.

GlycoT Therapeutics aims to apply its innovative and proprietary chemoenzymatic glycosylation technology for glycoengineering of therapeutic proteins such as monoclonal antibodies to improve their therapeutic efficacy.

Graphene Waves has been working on the cutting edge of graphene products. We developed large area and homogenous epitaxial graphene with high uniformity. Graphene Waves supplies graphene materials and quantum Hall effect devices to customers all around the world.

Haystack Solutions recognized the gaps in traditional approaches to recruiting, training, and workforce management in cybersecurity and changed the game with CyberGEN.IQ, the world’s only cybersecurity aptitude and talent assessment that transcends resumes and experience.

HighT-Tech designs, develops, and manufactures novel, advanced catalysts and battery materials. These new materials replace expensive legacy materials with stable, high-performance alternatives—accelerating production, improving durability, and lowering costs for critical applications in industrial and refinery operations and energy grid storage systems.

HOH Cells is the developer of a device for enhanced stem cell culture and banking, providing banked stem cells and their derivatives with better viability and quality.

Imagining Reality Insights & Solutions (IRIS) Reads is a reading intervention app in virtual reality (VR) that targets the foundational skills of reading. It uses multi-modal methods (sight, sound, and movement) to help struggling readers, including those with reading difficulties like dyslexia, learn letters, build words, acquire spelling rules, connect sight and sound, and ultimately achieve reading comprehension in an immersive and engaging environment.

InventWood transforms wood into high-performance building solutions that are stronger and lighter than steel that help builders create faster, reduce costs and turn cities into climate-wise carbon sinks.

ION Storage Systems has developed and is manufacturing a "no-swelling" fast-charging, solid-state lithium metal battery with ceramic based cathode agnostic architecture. This battery platform is engineered for performance in the toughest, most demanding environments—where safety, longevity, and energy density matter most.

IonQ is building the world’s best quantum computers to solve the world’s most complex problems.

LightSiNC NanoTech is providing customized design, fabrication and testing services for photonics chips from visible to infrared using silicon nitride and silicon carbide nanophotonics platforms. 

Living Canopies transformed urban spaces into smart green oases using plant based canopies to create shaded outdoor spaces.

Mblue Labs’ mission is to provide innovative solutions to address challenges in human aging. Mblue Labs has developed the first anti-aging skin technology with Methylene Blue. The product line Bluelene takes this innovation to market with a full face and body product line that neutralizes and reverses skin aging.

Maryland Energy and Sensor Technologies (MEST) is exploring, developing, and extending the applications of the thermoelastic cooling technology for commercial use across various industries, through patent filing and product development.

Medcura's novel hemostasis portfolio of products is created from natural, hydrophobically modified biomaterials designed to stop minimal, mild and moderate surgical bleeding. Medcura products achieve hemostasis by mechanical means, coating the bleeding site via the process of mucoadhesion.

MF Fire leverages their patented technologies, intelligent design, and state of the art fire science to build stoves with high efficiency and low emissions, while providing users with a simple, easy-to-use experience.

Mobile Comfort brings comfort and safety to environments where cooling is impractical.

N5 Sensors’ mission is to keep people safe from environmental hazards through a cloud-connected ecosystem of smarter sensors and by leveraging the endless possibilities of shared data and AI.

Through the engineering of precision biologics, NeuImmune will be positioned as the leading glycoprotein therapeutics company focused on addressing enzyme replacement therapies associated with unmet orphan disease conditions, starting with lysosomal storage disorders.

NewCopper develops state-of-art conductive inks from pristine or recycled copper that enable scalable, lean manufacturing of high performance, sustainable electronics. This breakthrough technology opens the door for new 3D printed electronics, flexible devices, biodegradable products, and many other exciting new applications.

Nodal Therapeutics is advancing microparticle-based lymph node therapies toward human clinical trials for autoimmune diseases.

At North American Wave Engine Corporation (NAWEC) we make affordable jet engines that require no moving parts. NAWEC leverages wave engine technology to produce simple jet engines with exceptional affordability and scalability.

OmniSpeech’s AI Audio Deepfake Detection system identifies AI-generated and manipulated voices in near real-time, providing a critical defense against voice fraud, misinformation, and synthetic media. 

Otomagnetics is developing a non-invasive method to  deliver drugs and other therapeutic payloads to inner and middle ear compartments, to the eye, and into the skin.

Pathotrak’s mission is to enable a world with fresher, safer food and make food outbreaks a thing of the past. We strive to eliminate food safety risks by providing cost-effective technologies that benefit producers, expedite processes for food-safety labs, and, most importantly, save lives.

Phasesfhit is pioneering the future of light with meta optics. Phaseshift provides end-to-end metasurface design and fabrication for, transforming complex optical systems into flat, lightweight, and multifunctional solutions.

Polymer-X upcycles plastic waste into fuels via electrothermal methods. Led by a group of materials scientists and chemical engineers, we are dedicated to developing and deploying innovative electrothermal methods for sustainable chemical manufacturing.

ProsightAI is on a mission to make medical-grade vital signs monitoring accessible anywhere, anytime, using nothing more than a standard camera. We're transforming how the world monitors health.

Recurrent Computing is developing a revolutionary approach to edge-computing based Machine Learning that is ideally suited to complex, time-varying environments, with the ability to make decisions or recommend actions rapidly.

Through RELAI agents—AI driven tools that actively identify and mitigate reliability issues—we empower you to ensure your AI models are accurate, trustworthy, and dependable.

Reversal Therapeutics is a preclinical stage biopharmaceutical company pioneering the development of proprietary molecules designed to neutralize and remove a wide range of agents from the body through a revolutionary sequestration mode of action.

SecondWrite detects zero-day malware with few false positives, and when needed – provides detailed actionable intelligence on malware.

SentiMetrix provides a real‐time, highly accurate, multilingual product that provides a fine‐grained lens into how sentiments about a brand, product, individual, or company are changing over time. Our clients include financial institutions, government agencies, and consumer brands.

SIlvec envisions a world where trees can be vaccinated and cured like humans, without the need to alter their genomes.Silvec has developed the first method for vaccinating trees using breakthrough RNA therapy.

Technik uses innovative equipment, technology, and services to redefine the individual training experience of soccer athletes , empowering them to take full control of their development and future. 

Transmucosis has built the only protein-based vaccination platform that will activate both mucosal and systemic branches of the immune system

USPlasma leverages the fourth state of matter, plasmas, and ultra-high temperature, up to and above the sun’s surface temperature, to manufacture cost-competitive, high quality, and novel materials and to minimize, recycle, and treat waste to ensure a clean environment.

Ventoscity is developing wearable sensors to help individuals measure and moderate gut health.

VersaVolt batteries convert seawater and oxygen into energy.

VisiSonics provides industry leading acoustic measurement and visualization solutions for NVH (Noise, Vibration and Harshness), industrial noise detection and noise mitigation for critical listening spaces.

At Wh-Power, we're on a mission to redefine the future of energy storage through groundbreaking innovations in battery technology. Wh-Power battery products leverage innovative interhalogen technology to deliver 5X energy density at a low cost, ensuring unparalleled stability and safety across a wide temperature range